Education and Training
THRIVE Feasibility Trial
To evaluate the feasibility of a pragmatic, large scale, comparative effectiveness, randomized evaluation of patient experience of intravenous propofol versus inhaled volatile anesthesia.
Stanford is currently not accepting patients for this trial.
Stanford Investigator(s):
Intervention(s):
- other: Anesthetic technique Propofol TIVA
- other: Anesthetic technique inhaled agent
Eligibility
Inclusion Criteria:
- 18 years or older
- Undergoing elective non-cardiac surgery expected to last ≥ 60 min requiring general
anesthesia, including a tracheal tube or laryngeal mask airway (or similar
supra-glottic device)
Exclusion Criteria:
- Inability to provide informed consent in English
- Pregnancy (based on patient report or positive test on the day of surgery)
- Surgical procedure requiring general, regional, neuraxial anesthesia administered by
an anesthesia clinician (anesthesiologist, CRNA, anesthesiology assistant) occurring
within 30 days prior to or planned to occur within 30 days after surgery date
- Contraindication to propofol TIVA or inhaled volatile (for example, documented allergy
to propofol, history of severe postoperative nausea or vomiting, concern for or
history of malignant hyperthermia)
- Surgical procedures requiring specific general anesthesia option (for example, TIVA
required for neuromonitoring).
- Hospital approved, written protocol mandating a particular technique
- History of intraoperative awareness during general anesthesia based on patient
self-report on the day of consent
- Planned postoperative intubation
Ages Eligible for Study
18 Years - N/A
Genders Eligible for Study
All
Not currently accepting new patients for this trial
Contact Information
Stanford University
School of Medicine
300 Pasteur Drive
Stanford,
CA
94305
Larry Chu, MD, MS
Not Recruiting