Education and Training

Topical Insulin for Glaucoma

The purpose of this Phase 1 trial is to determine the safety over 1-2 months of topic sterile human recombinant insulin on subjects with optic neuropathies (glaucoma, ischecmic optic neuropathy, and optic disc drusen).

Stanford is currently accepting patients for this trial.

Stanford Investigator(s):

Intervention(s):

  • drug: Insulin, 4 units
  • drug: Insulin, 20 units

Eligibility


Inclusion Criteria:

   - Capable to provide informed consent

   - Diagnosis of optic neuropathy either glaucoma or NAION or optic disc drusen.

   - Only one eye per patient will be selected as the study eye - if both eyes meet the
   inclusion criteria, the eye with the worse acuity and /or visual field will be
   selected. The contralateral eye will be left untouched.

Exclusion Criteria:

   - Pregnant or breastfeeding woman

   - Presence of any ocular pathologies other than glaucoma that contributes to the severe
   vision loss (retinopathy / maculopathy, severe uveitis, keratopathy, etc.)

   - Diagnosis of glucose intolerance, type 1 or 2 diabetes mellitus

   - Inability to perform reliable visual field

   - Unable to provide informed consent

   - Unable to complete the tests and follow-ups required by the study

Ages Eligible for Study

18 Years - N/A

Genders Eligible for Study

All

Now accepting new patients

Contact Information

Stanford University
School of Medicine
300 Pasteur Drive
Stanford, CA 94305
Esther Elenes
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