Education and Training
Magnesium for Peroral Endoscopic Myotomy
Postoperative pain after peroral endoscopic myotomy occurs due to involuntary esophageal smooth muscle spasms. Magnesium has antispasmodic properties as a smooth muscle relaxant. This study hypothesizes that among patients having peroral endoscopic myotomy, magnesium will decrease postoperative esophgeal pain as measured by the esophageal symptoms questionnaire, while decreasing perioperative opioid requirements.
Stanford is currently not accepting patients for this trial.
Stanford Investigator(s):
Intervention(s):
- drug: Magnesium sulfate
- drug: Normal Saline
Eligibility
Inclusion Criteria:
- Planned peroral endoscopic myotomy procedure
Exclusion Criteria:
- cannot give consent
- patients who are clinically unstable and/or require urgent/emergent intervention
- previous esophageal myotomy
- preexisting hypermagnesemia
- end-stage renal disease
- neuromuscular disease, including but not limited to Guillain-Barre syndrome,
myasthenia gravis, congenital myopathy, and muscular dystrophy
- preexisting heart failure
- severe ventricular systolic dysfunction (left or right ventricle)
Ages Eligible for Study
18 Years - N/A
Genders Eligible for Study
All
Not currently accepting new patients for this trial
Contact Information
Stanford University
School of Medicine
300 Pasteur Drive
Stanford,
CA
94305
Richard K Kim, MD
347-586-9661
Not Recruiting