Education and Training

Bone Marrow Sparing Image-Guided Radiation Therapy (RT) Incorporating Novel Use of GCSF and FDG-PET Imaging

This is a research study using Granulocyte Colony Stimulating Factor (GCSF) as a bone marrow stimulating agent for imaging to guide radiation treatment planning. G-CSF is a type of growth factor. Growth factors are proteins made in the body. G-CSF is a type of growth factor that makes the bone marrow produce white blood cells to reduce the risk of infection after some types of cancer treatment.

Stanford is currently accepting patients for this trial.

Stanford Investigator(s):

Intervention(s):

  • diagnostic test: FDG PET/CT
  • drug: GCSF

Eligibility


Inclusion Criteria:

   - 2018 international Federation of Gynecology and Obstetrics (FIGO) stage I IIIC1 cervix
   cancer with no prior treatment or stage IIIA IIIC1 endometrial cancer status post
   hysterectomy and lymph node assessment

   - No required para aortic or extended field radiation

   - Eastern Cooperative Oncology Group (ECOG) performance status 0 2

   - Adequate kidney function (serum Cr <1.5 or creatinine clearance >50 mg/dl)

   - Adequate bone marrow function (white blood cells > 3.0 X 109/L, platelets >100 x
   109/L)

   - Ability to understand and the willingness to sign a written informed consent document.

Exclusion Criteria:

   - Treatment for other cancer in the past 2 years

   - Previous pelvic radiation

   - Medical condition that prevents receiving chemotherapy

Ages Eligible for Study

18 Years - N/A

Genders Eligible for Study

Female

Now accepting new patients

Contact Information

Stanford University
School of Medicine
300 Pasteur Drive
Stanford, CA 94305
Neha Aidasani
650-721-4076
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