Education and Training

Immune and Physical Recovery Following Cesarean Delivery

Pregnancy results in an altered immune state compared to the nonpregnant population. A significant proportion of women undergoing cesarean delivery recover poorly. The first step to determining whether this is an immune driven / associated process is to characterise what effects this surgery has on maternal immune function. "Normal" changes will be evaluated in maternal immune function and activity precipitated by surgery and delivery of the neonate. Immune response to surgery will be compared to historical immune data from patients undergoing non-obstetric surgery (orthopaedic patients).

Stanford is currently not accepting patients for this trial.

Stanford Investigator(s):

Intervention(s):

  • procedure: Elective cesarean delivery

Eligibility


Inclusion Criteria:

   - elective cesarean delivery at Lucile Packard Hospital

   - age >20 to <50 years old,

   - single pregnancy term

   - gestational age 37-41 weeks pregnancy,

   - elective cesarean delivery,

   - spinal or combined spinal-epidural anesthesia as primary anesthesia mode,

   - multimodal analgesia regimen (including intrathecal morphine and regular acetaminophen
   and NSAIDs), single center at Stanford.

   - ASA grade 1 or 2.

   - gestational diabetes (not requiring insulin or diabetes medications and pre-eclampsia
   (without severe features) will be included.

   - ethnic background: all ethnic backgrounds will be included gender: pregnant women only

Exclusion Criteria:

   - refusal to participate

Ages Eligible for Study

18 Years - 50 Years

Genders Eligible for Study

Female

Not currently accepting new patients for this trial

Contact Information

Stanford University
School of Medicine
300 Pasteur Drive
Stanford, CA 94305
Not Recruiting