Inclusion Criteria:

   - Subjects with suspected brain tumors undergoing surgical removal as their standard of
   care will be eligible. These may include subjects status post chemotherapy and/or
   radiation or subjects who have undergone diagnostic biopsy for their original
   diagnosis and are felt to be candidates for resection.

   - Subjects must be eligible for resection as determined by the operating surgeon.

   - Planned standard of care surgery

   - Subject age 6 months to 25 years

   - Life expectancy of more than 12 weeks

Exclusion Criteria:

   - Received an investigational drug within 30 days prior to first dose of Panitumumab
   IRDye800

   - Myocardial infarction (MI); cerebrovascular accident (CVA); uncontrolled congestive
   heart failure (CHF); significant liver disease; or unstable angina within 6 months
   prior to enrollment

   - History of infusion reactions to monoclonal antibody therapies

   - Pregnant or breastfeeding

   - Evidence of QTc prolongation on pretreatment ECG (greater than 440 ms in children 1 8
   years or 8 to 18 year old males or greater than 460 ms in infants up to 1 year or 8 to
   18 year old females)

   - Magnesium, potassium and calcium < the lower limit of normal per institution normal
   lab values

   - Serum creatinine > 1.5 times upper reference range

   - Other lab values that in the opinion of the primary surgeon would prevent surgical
   resection

   - Subjects receiving Class IA (quinidine, procainamide) or Class III (dofetilide,
   amiodarone, sotalol) antiarrhythmic agents.

   - Subjects with a history or evidence of interstitial pneumonitis or pulmonary fibrosis

   - Subjects not deemed to be appropriate candidates for optimal resection of tumor based
   on location, involvement of eloquent brain, satellite lesions, or other factors not
   specifically listed here