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EDRN Prostate MRI Biomarker Study

The commercialization of MRI fusion biopsies has resulted in a dramatic increase in the use of MRI imaging for prostate cancer. How best to use MRI in the initial prostate biopsy setting given the availability of validated prostate cancer early detection markers is uncertain.This study will allow investigators to determine if prostate MRI is superior to validated panel of laboratory biomarkers (e.g. PCA3, PSA and TMPRSS2:ERG) in the initial biopsy setting.

Stanford is currently accepting patients for this trial.

Stanford Investigator(s):

Intervention(s):

  • diagnostic test: MRI prostate

Eligibility


Inclusion Criteria:

   - Men with suspected but undiagnosed prostate cancer

   - To be scheduled/scheduled for biopsy as routine clinical care

Exclusion Criteria:

   - Inability to obtain blood and urine per SOP or conduct an attentive DRE

   - Unable to undergo/tolerate a prostate MRI or failure to conduct the MRI

   - Prior diagnosis of prostate cancer

   - Prior prostate MRI unless being used as Index MRI (in this case index MRI can be one
   year prior to consent date)

   - Participating in clinical trial for prostate disease

   - Prior prostate surgery such as TURP, TUNA, TUMT, HOLEP, REZUM, UROlift

   - Prior PCA3, TMPRSS2:erg or MIPS panel performed for clinical purpose

Ages Eligible for Study

18 Years - N/A

Genders Eligible for Study

Male

Now accepting new patients

Contact Information

Stanford University
School of Medicine
300 Pasteur Drive
Stanford, CA 94305
Daniel Alvarez
650-723-0948
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