Education and Training
Effect of Different Skin Creams on TEWL
Prospective, single center, clinical pilot study to test the hypothesis that lipid rich EpiCeram® is superior in improving skin barrier function compared to Aveeno Daily Moisturising Sheer Hydration Lotion®.
Stanford is currently not accepting patients for this trial.
Stanford Investigator(s):
Intervention(s):
- drug: EpiCeram
- drug: Aveeno Daily Moisturising Sheer Hydration Lotion®
Eligibility
Inclusion Criteria:
1. Parent guardian must be able to understand and provide informed consent per
Institutional Review Board (IRB) guidelines and regulations.
2. Male or female participants, between the ages of 0 to 40 years will be included
3. Diagnosis of moderate to severe active AD (Scoring Atopic Dermatitis (SCORAD) score >
26) without a history or current manifestations of eczema herpeticum (EH)
4. AD affecting at least 3 different skin areas (contralateral arms and one lower
extremity)
Exclusion Criteria:
1. Inability or unwillingness of a parent guardian to give written informed consent, or
to comply with study protocol.
2. Participants with skin disease other than AD that might compromise the stratum corneum
barriers (e.g., bullous diseases, psoriasis, cutaneous T-cell lymphoma (also called
Mycosis Fungoides or Sezary syndrome], dermatitis herpetiformis, Hailey-Hailey, or
Darier's disease).
3. Known or suspected immunosuppression
4. Severe concomitant illness(es)
5. History of serious life-threatening reaction to latex, tape, or adhesives
6. Has received total body phototherapy (e.g., ultraviolet light B [UVB], psoralen
ultraviolet light A [PUVA], tanning beds [>1 visit per week]) within 30 days of the
Enrollment Visit
7. Use of topical corticosteroids, topical immunomodulatory agents (such as calcineural
inhibitors and crisaborole), or topical antibiotics on the upper or lower extremities
within 7 days of the Enrollment Visit
8. Has taken a bleach bath within 7 days of the Enrollment Visit
9. Use of systemic antibiotics, antiparasitics, antivirals, or antifungals within 7 days
of the Enrollment Visit.
Ages Eligible for Study
1 Day - 40 Years
Genders Eligible for Study
All
Not currently accepting new patients for this trial
Contact Information
Stanford University
School of Medicine
300 Pasteur Drive
Stanford,
CA
94305
Not Recruiting