Education and Training
PET/MRI in the Diagnosis of Chronic Pain
Several studies have implicated involvement of sigma-1 receptors (SR1s) in the generation of chronic pain, while others are investigating anti SR1 drugs for treatment of chronic pain. Using [18F]-FTC-146 and positron emission tomography/magnetic resonance imaging (PET/MRI), the investigators hope to identify the source of pain generation in patients with chronic pain. The purpose of this study is to compare the uptake of [18F]FTC-146 in healthy volunteers to that of individuals suffering from chronic pain.
Stanford is currently accepting patients for this trial.
Stanford Investigator(s):
Intervention(s):
- drug: [18F]FTC-146
Eligibility
Inclusion Criteria:
Healthy Volunteers:
1. At least 18 years old.
2. Covid Vaccination status: Vaccinated or unvaccinated subjects who received a negative
test result from the Covid test within 72 hours of the scan.
Pain Patients:
1. At least 18 years old.
2. Chronic pain (nociceptive, neuropathic or mixed pain) lasting greater than 2 months.
3. Pain level of at least 4/10 on a 0-10 Comparative Pain Scale.
4. Covid Vaccination status: Vaccinated or unvaccinated subjects who received a negative
test result from the Covid test within 72 hours of the scan.
Exclusion Criteria:
Healthy Volunteers:
1. Pain
2. Pain Medication
3. MRI incompatible
4. Pregnant or nursing
5. Non-English speaker
6. Claustrophobic
Pain Patients:
1. MRI incompatible
2. Pregnant or nursing
3. Non-English speaker
4. Claustrophobic
Ages Eligible for Study
18 Years - N/A
Genders Eligible for Study
All
Now accepting new patients
Contact Information
Stanford University
School of Medicine
300 Pasteur Drive
Stanford,
CA
94305
Adrian Valladarez, BA
I'm interested