Key Inclusion Criteria:

   - The subject is capable of understanding and complying with protocol requirements.

   - The subject or the subject's legally acceptable representative signs and dates a
   written, informed consent/assent form and any required privacy authorization prior to
   the initiation of any study procedures.

   - Subject has a documented genetic mutation consistent with EBS.

   - Subject has completed study CCP-020-301 or participated in study CCP-020-101.

   - Subject/caregiver agrees to report use of any topical therapies applied to EBS lesions

   - If the subject is a woman of childbearing potential, she has a negative urine
   pregnancy test and agrees to use an approved effective method of birth control, for
   the duration of the study.

   - Subject is non-lactating and is not planning for pregnancy during the study period.

   - Subject is willing and able to follow all study instructions and to attend all study
   visits.

Key Exclusion Criteria:

   - Subject has EBS lesions to be treated that are infected

   - Subject has evidence of a systemic infection or has used systemic antibiotics within 7
   days prior to Baseline Visit.

   - The subject was discontinued from the feeder study due to an adverse event judged to
   be related or possibly related to the study medication.

   - Subject has experienced a change in clinical status from the feeder study that puts
   the subject at undue risk to participate.