Education and Training

Gastric Acid Suppression and Probiotic Colonization

Probiotics are over-the-counter dietary products with microorganisms that are generally consumed for health benefit. However, the durability of these microorganisms is unclear, particularly when they pass through the highly acidic environment of the stomach. We will test the colonization of these microorganisms among individuals who consume probiotics with and without acid suppression therapy.

Stanford is currently not accepting patients for this trial.

Intervention(s):

  • drug: Omeprazole
  • dietary supplement: VSL #3
  • drug: Placebo

Eligibility


Inclusion Criteria:

   - Healthy volunteers ages 18 years and ≤ 75 years.

   - Able to visit the study Doctor's office 3 times, answer 3 questionnaires, and provide
   stools and blood samples.

Exclusion Criteria:

   - Gastric cancer, Barrett's esophagus cancer, any gastrointestinal condition, or soy or
   gluten sensitivity

   - Previous abdominal surgery

   - Currently pregnant or nursing

   - Had H. Pylori Infection

   - Diagnosed with any chronic medical condition other than hypertension or hyperlipidemia

   - Currently consuming herbs or probiotics

Ages Eligible for Study

18 Years - 75 Years

Genders Eligible for Study

All

Not currently accepting new patients for this trial

Contact Information

Stanford University
School of Medicine
300 Pasteur Drive
Stanford, CA 94305
Berkeley Limketkai
650-736-0431
Not Recruiting