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Efficacy and Safety of Ethanol Lock Therapy for the Prevention of Central Line-associated Bloodstream Infections

Patients on long-term parenteral nutrition (PN) are at high risk for central line-associated bloodstream infections (CLABSI). This study evaluates the efficacy and safety of ethanol lock therapy for CLABSI prophylaxis in adult patients on PN.

Stanford is currently not accepting patients for this trial.

Intervention(s):

  • other: Ethanol lock
  • other: Heparin lock

Eligibility


Inclusion Criteria:

   - Adult patients (ages 18-80) on PN with silicone-based central venous catheters

Exclusion Criteria:

   - Weight ≤ 50 kg

   - Allergy/hypersensitivity/intolerance to ethanol or heparin

   - Pregnancy or breastfeeding

   - Patient taking metronidazole, disulfiram, or isoniazid

   - History of alcohol abuse

   - History of heparin-induced thrombocytopenia (HIT) or have an active hypocoagulable
   state

Ages Eligible for Study

18 Years - 80 Years

Genders Eligible for Study

All

Not currently accepting new patients for this trial

Contact Information

Stanford University
School of Medicine
300 Pasteur Drive
Stanford, CA 94305
Sheila Bautista
650-736-0431
Not Recruiting