Education and Training
Management of Palmar Hyperhidrosis With Hydrogel-based Iontophoresis
This study will evaluate the use of hydrogel electrode pads (rather than tap water baths) to deliver iontophoresis treatment using a traditional iontophoresis device. Participants will treat one hand with the hydrogel-based iontophoresis device and leave the other hand untreated.
Stanford is currently not accepting patients for this trial.
Stanford Investigator(s):
Intervention(s):
- device: Hydrogel electrode-based iontophoresis
- device: Hydrogel electrode-based iontophoresis
Eligibility
Inclusion Criteria:
- 13 years of age or older
- >6 months self-reported history of primary palmar hyperhidrosis
- Initial gravimetry test: >20mg/min on each palm
- No topical treatments for hyperhidrosis (antiperspirants) on the palms for 2 weeks
prior to the start of the study
- No systemic treatments for hyperhidrosis (anticholinergics) for 4 weeks prior to the
start of the study
- No tap water iontophoresis treatment for 6 weeks
- No Botox injections on the palms for 6 months (if single treatment session) or 10
months (if >1 previous sessions) prior to the start of the study
- No history of cardiothoracic sympathectomy for hyperhidrosis
- Able to attend 3 office visits (Stanford Medical Outpatient Center located at 450
Broadway St, Redwood City, CA 94063; Lucile Packard Children's Hospital at 730 Welch
Road, 1st Floor, Palo Alto, CA 94304) and one virtual visit in an 8 week time frame
- Capable of performing sweat level testing and hydrogel-based iontophoresis treatment
at home, after training
- Hydrogel electrode pad fits on the hand (typically tip of middle finger to lower end
of palm length of 6.5in (16.5cm) or greater)
Exclusion Criteria:
- Patients with implanted electronic medical devices e.g. pacemaker, implantable
cardioverter/defibrillator)
- Patients with metal implants in the extremity that will be treated
- Patients with larger skin defects (on the palm or arm of the extremity that will be
treated) that cannot be covered by petroleum jelly
- Pregnant or nursing women, or looking to become pregnant
- Patients on medications that interfere with neuroglandular transmission
- Patients with active infection locally or systemically
- Patients with history of contact dermatitis to acrylates
- Patients with history of contact or systemic allergy to iodine
- Patients with a history of ischemic heart disease, cardiac arrhythmias, epilepsy or
thyroid disease
Ages Eligible for Study
13 Years - N/A
Genders Eligible for Study
All
Not currently accepting new patients for this trial
Contact Information
Stanford University
School of Medicine
300 Pasteur Drive
Stanford,
CA
94305
Veronique Peiffer, PhD
Not Recruiting