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Pediatric ACL: Understanding Treatment Options

Pediatric ACL: Understanding Treatment Outcomes (PLUTO) is a multi-center, prospective cohort study. Specific aims of PLUTO are to evaluate the safety and comparative effectiveness of non-operative treatment, as well as four operative treatments including (1) transphyseal ACL reconstruction (2) partial transphyseal ACL reconstruction, (3) physeal-sparing epiphyseal ACL reconstruction using the Anderson technique, and (4) physeal-sparing ACL reconstruction using the Micheli/Kocher technique in prepubescent and pubescent skeletally immature patients.

Stanford is currently accepting patients for this trial.

Stanford Investigator(s):

Intervention(s):

  • other: Non-operative treatment group will undergo standardized treatment which will include rehabilitation, bracing and certain activity restrictions
  • procedure: Surgical technique: Transphyseal reconstruction
  • procedure: Surgical technique: Partial transphyseal reconstruction
  • procedure: Surgical technique: Physeal sparing reconstruction by the Anderson method
  • procedure: Surgical technique: Physeal sparing reconstruction by the Micheli/Kocher method

Eligibility


Inclusion Criteria:

   - Diagnosis of complete intrasubstance ACL tear

   - Skeletally Immature (by knee radiographs)

Exclusion Criteria:

   - Prior ACL surgery on the ipsilateral knee

   - Congenital ACL deficiency

   - Multiple ligament reconstruction required

   - Other significant comorbidities including syndromic conditions, neuromuscular
   disorders or developmental delay

   - If scheduling of the ACL surgery is impacted by the skeletal maturity of the patient

   - Simultaneous bilateral ACL tears

Ages Eligible for Study

5 Years - 18 Years

Genders Eligible for Study

All

Now accepting new patients

Contact Information

Stanford University
School of Medicine
300 Pasteur Drive
Stanford, CA 94305
Steven Frick, MD
Recruiting