Education and Training

Inhaled Nitric Oxide and Inhaled Prostacyclin After Cardiac Surgery for Heart Transplant or LVAD Placement

Research study evaluating the individual and combined effects of inhaled nitric oxide (iNO) and inhaled prostacyclin (iPGI2), on the function of the right heart after surgery for either heart transplant or for left ventricular assist device (LVAD) placement. The investigators hope to learn if these two medications, when given together after surgery, improve right heart function by lowering blood vessel pressures in the lungs. The investigators hope to learn if the combined effects of these two medications are better than either medication used alone. Participants were selected as a possible participant in this study because right heart problems are common during and after surgery for heart transplant and for LVAD placement. In addition, iNO is always given during and after these two types of surgeries at Stanford to help improve how the right heart functions.

Stanford is currently not accepting patients for this trial.

Intervention(s):

  • drug: Nitric Oxide
  • drug: Prostacyclin

Eligibility


Inclusion Criteria:

   - Adult cardiac surgical patients scheduled to undergo either heart transplantation or
   LVAD placement

Exclusion Criteria:

   - Patients with prior documented allergic reactions or intolerance to either nitric
   oxide or prostacyclin will be excluded. Patients not undergoing heart transplantation
   or LVAD placement will be excluded.

Ages Eligible for Study

18 Years - N/A

Genders Eligible for Study

All

Not currently accepting new patients for this trial

Contact Information

Stanford University
School of Medicine
300 Pasteur Drive
Stanford, CA 94305
Andrew J Powers, MD
734-751-5949
Not Recruiting