Education and Training
Personal Genomics for Preventive Cardiology
The purpose of this study is to see if providing information to a person on their inherited (genetic) risk of cardiovascular disease (CVD) helps to motivate that person to change their diet, lifestyle or medication regimen to alter their risk.
Stanford is currently not accepting patients for this trial.
Stanford Investigator(s):
Intervention(s):
- behavioral: genetic risk score for coronary risk factors
Eligibility
Inclusion Criteria:
- Adults age > 18
- Patient seeking cardiovascular risk evaluation
- At intermediate (6-20%) or high risk (> 20%) over 10 years of CAD as defined by
Framingham 10 year risk score AND/OR at > 20% risk of CAD over 30 years using the
Framingham 30 year risk calculator
- The genetic risk factors have been evaluated predominantly in white/European subjects.
However, there is considerable overlap in the genetic architecture of South Asians and
Hispanic/Latino populations. Therefore, we will limit our initial studies to these
three race/ethnicity groups.
Exclusion Criteria:
- History of myocardial infarction, angina, stroke, peripheral arterial disease, PCI, or
CABG
- Already on lipid lowering therapy
- Anticipated survival <1 year (e.g. metastatic cancer)
- Serious conditions that would limit ability to adhere to recommendations (inability to
take statins, exercise)
- Already had genetic testing
- Concurrent enrollment in another clinical trial
- Pregnant or breastfeeding
Ages Eligible for Study
18 Years - N/A
Genders Eligible for Study
All
Not currently accepting new patients for this trial
Contact Information
Stanford University
School of Medicine
300 Pasteur Drive
Stanford,
CA
94305
Josh Knowles
650-804-2526
Not Recruiting