Education and Training

Performance-Enhancing Effects of Platelet-Rich Plasma (PRP) Injections

Platelet-Rich Plasma (PRP) has been banned in competitive athletes because some people think it may enhance athletic performance. However, there is very little published research to support or undermine this point of view. The purposes of this study are: (1) To assess the effects of local platelet-rich plasma (PRP) therapy on systemic levels of growth factors with suspected or known performance-enhancing effects; and (2) To understand whether the effect of PRP therapy on these growth factors differs between intramuscular and intratendinous PRP injections.

This research study is looking for 40 people who are receiving platelet-rich plasma therapy for a tendon or muscle injury. The study involves collecting seven blood samples (2 teaspoons each) from each patient, before and after the PRP treatment. Blood samples may be donated at any location of the patient's choosing, and participants will be paid for their time.

Stanford is currently not accepting patients for this trial.

Intervention(s):

  • procedure: Platelet-Rich Plasma (PRP)
  • procedure: Ultrasound-guided platelet-rich-plasma (PRP) injection

Eligibility


Inclusion Criteria:

   - Male and female patients 18-50 years old, receiving ultrasound-guided intratendinous
   or intramuscular PRP injections

Exclusion Criteria:

   - History of cancer, diabetes, hormone-replacement therapy, or abnormal nutritional
   habits.

   - Contraindications for PRP therapy itself:

      - preexisting coagulation defects including thrombocytopenia

      - hypofibrinogenemia

      - anticoagulation medications

      - hypersensitivity to bovine products, which may be used for platelet activation.

Ages Eligible for Study

N/A - N/A

Genders Eligible for Study

All

Not currently accepting new patients for this trial

Contact Information

Stanford University
School of Medicine
300 Pasteur Drive
Stanford, CA 94305
Amy S Wasterlain
718-644-5731
Not Recruiting