Education and Training
Study of Treatment for Adolescents With Bulimia Nervosa
In the face of scant literature on the subject, the investigators aim to more clearly identify effective treatments for adolescent bulimia nervosa (BN) through a treatment study comparing two current treatments (Cognitive Behavioral Therapy for Adolescents, CBT-A and Family Based Therapy for Bulimia Nervosa, FBT-BN) for the disorder in comparison with a non-specific therapy, Supportive Psychotherapy for Adolescent Bulimia (SPT). Additionally, the investigators hope to provide clinicians with information on treatment efficacy, variables that might influence outcome, and processes that may affect treatment efficacy that will guide them in their efforts to treat adolescent BN.
Stanford is currently not accepting patients for this trial.
Stanford Investigator(s):
Intervention(s):
- behavioral: Cognitive Behavioral Therapy for Adolescents
- behavioral: Supportive Psychotherapy
- behavioral: Family Based Therapy for Bulimia Nervosa
Eligibility
Inclusion Criteria:
1. Participants will be adolescents living with at least one of their parents and between
the ages of 12 and 18 years of age with a DSM IV diagnosis of BN or partial BN (binge
eating and purging at least one time per week over a six month period).
2. Males meeting inclusion criteria will also be entered into the study. They must have
age-adjusted BMI greater than 17.5, or ideal body weight (IBW) > 85%.
3. Family, for the purposes of this study, includes members of the subject's household,
including at least one parent or adult guardian. Single parent families, divorced
families, step-parents, and other types of families will be allowed to enter the
study.
Exclusion Criteria:
1. psychotic illness or other mental illness requiring hospitalization; bipolar I
disorder, depression with active suicidal thoughts and behavior;
2. associated physical illness that necessitates hospitalization;
3. current dependence on drugs or alcohol;
4. current diagnosis of anorexia nervosa or weight less that 85% IBW;
5. physical conditions (e.g. diabetes mellitus, pregnancy) known to influence eating or
weight;
6. currently taking medication for co-morbid conditions for less than 2-months;
7. currently taking medications that may induce weight loss, e.g., appetite suppressants
such as sibutramine, phentermine, and xenical, unless the participant is willing to
withdraw from such medications;
8. currently taking medications for symptoms of BN and unwilling to discontinue these
prior to initiating treatment in the study
9. previous CBT or FBT treatment for BN
10. married subjects
11. emancipated minors
12. family members will be excluded from engaging in treatment for the following reasons:
- Current or history of sexual or physical abuse of the patient by family members.
Perpetrators of the abuse will be excluded from treatment. Should sexual or
physical abuse by a family member occur during the course of treatment,
perpetrators will be excluded from ongoing treatment.
- Substance dependence, psychosis, or severe medical illness that would limit full
participation in therapy, or that might put the family member at risk for
worsening of their condition during treatment. The decision whether or not to
allow these individuals to continue to participate in treatment will be made by
the therapist in consultation with the treatment supervisor.
Ages Eligible for Study
12 Years - 18 Years
Genders Eligible for Study
All
Not currently accepting new patients for this trial
Contact Information
Stanford University
School of Medicine
300 Pasteur Drive
Stanford,
CA
94305
James Lock, MD, PhD
650-723-5473
Not Recruiting