Education and Training

Effect of Fish Oil on Plasma Triglycerides in Adults

The purpose of this small, short pilot study is to determine the feasibility (e.g., recruitment, dose acceptance, retention) of a future longer trial comparing the effects of two types of omega-3 fats from fish oil on plasma triglycerides. The two types of fish oil are composed of (1) omega-3 fatty acids in triglyceride form; and (2) as esterified free fatty acids (i.e. ethyl esters). Although these two types of fish oil supplements are available to the public, it remains unclear whether they are equally effective in lowering plasma triglycerides.

Stanford is currently not accepting patients for this trial.

Stanford Investigator(s):

Intervention(s):

  • dietary supplement: Fish oil (90% triglycerides)
  • dietary supplement: Fish oil (60% triglycerides)
  • dietary supplement: Fish oil (ethyl esters)
  • dietary supplement: Soy oil

Eligibility


Inclusion Criteria:*Gender: Both women and men

   - Age: > or = 18 years

   - Ethnicity and race: All ethnic and racial backgrounds welcome

   - Fasting blood triglycerides greater than or equal to 150 mg/dL

   - Planning to be available for clinic visits for the 12 weeks of study participation

   - Ability and willingness to give written informed consent

   - No known active psychiatric illness. Exclusion Criteria:*At screening:

   - Daily intake of dietary supplements containing omega-3 FAs within the past month.

   - Fasting blood glucose greater than or equal to 126 mg/dL

   - Self reported personal history of:

   - Clinically significant atherosclerosis (e.g., CAD, PAD)

   - Malignant neoplasm

   - Subjects currently receiving the following medications (self report):

   - Lipid lowering drugs including statins

   - Anti-hypertensive drugs: beta-blockers and thiazides

   - Body Mass Index (BMI) greater than or equal to 40.

   - Pregnant or Lactating

   - Inability to communicate effectively with study personnel

Ages Eligible for Study

18 Years - N/A

Genders Eligible for Study

All

Not currently accepting new patients for this trial

Contact Information

Stanford University
School of Medicine
300 Pasteur Drive
Stanford, CA 94305
Antonella Dewell
6507368577
Not Recruiting