Education and Training
Outcomes Following Myocardial Revascularization: On and Off Cardiopulmonary Bypass
Ischemic heart disease is one of the most frequent diagnoses in the VA system. Moreover, 5,819 coronary artery bypass graft (CABG-only) procedures were performed in the VA in Fiscal Year (FY) 1999. Throughout VA and non-VA cardiac surgery programs nationwide, myocardial revascularization is now being performed using two surgical techniques. One technique is performed with cardiopulmonary bypass (CPB) usually with cardioplegic arrest ("on-pump") and the other without CPB on a beating heart ("off-pump"). The overall purpose of this proposed randomized, controlled, clinical trial is to rigorously evaluate the impact of using an on-pump versus off-pump surgical technique for coronary artery bypass graft (CABG-only) procedures (performed with a traditional median sternotomy incision) upon patient clinical outcomes and resource utilization.
Stanford is currently not accepting patients for this trial.
Stanford Investigator(s):
Intervention(s):
- procedure: Coronary artery bypass - on-pump
- procedure: Coronary artery bypass - off-pump
Eligibility
Inclusion Criteria:
- Elective or Urgent CABG
- CABG only procedure to be performed
Exclusion Criteria:
- Patient's surgeon is not a participant that meets study off-pup criteria
- Valve or Valve/CABG procedure
- Emergent, hemodynamically unstable, or in cardiogenic shock preoperatively
- Moderate, moderate, to severe, or severe valvular disease
- Enrolled in another therapeutic or interventional study
- Majority of diffusely diseased distal vessels
- Clinical Care Team has reservations
- History of on-compliance
- Patient preference for treatment arm
- Inability to provide informed consent
Ages Eligible for Study
N/A - N/A
Genders Eligible for Study
All
Not currently accepting new patients for this trial
Contact Information
Stanford University
School of Medicine
300 Pasteur Drive
Stanford,
CA
94305
Not Recruiting