Stanford School of Medicine
Radiation Oncology

Louis Lee


Ph.D. in Medical Physics,
The Hong Kong Polytechnic University,
Hong Kong, 2005

Research

My PhD project was to develop a spectral microdensitometer for analyzing radiochromic film in view of that no existing densitometer has been designed with commensurate capabilities to exploit the radiochromic film to its full potential in the field of high-resolution film dosimetry. A novel readout and measurement algorithm has also been proposed to maximize the sensitivity of the radiochromic film. The high-resolution radiochromic film dosimetry realized by this project has been successfully applied in verifying small-field stereotactic radiosurgery, on sub-millimeter order, of which the verification always presents problematic issues in conventional methodologies. A US patent has been granted to the design of the microdensitometer and another patent on the readout algorithm is pending. For my postdoctoral research in Stanford, I work with Dr. Xing mainly on the dose reconstruction in Cone Beam Computed Tomography (CBCT), respiratory-correlated CBCT and the exploration of their clinical usefulness on Adaptive Radiation Therapy.



Patents



Publications

  1. Lee K.Y., Fung K.K.L. and Kwok C.S. (2006). "Application of high-resolution radiochromic film dosimetry in a small-field stereotactic radiosurgery plan". Applied Radiation and Isotopes, 64:934-939.
  2. Lee K.Y. and Fung K.K.L. (2006). "Radiation dose measurement for radiochromic films based on measurements at multiple absorption peaks". The Hong Kong Polytechnic University. 11/403,677. US Patent pending.
  3. Lee K.Y., Fung K.K.L. and Kwok C.S. (2005). "Dual-peak dose measurement for radiochromic films by a newly developed spectral microdensitometer". Medical Physics, 32: 1485-1490.
  4. Lee K.Y. and Kwok C.S. (2005). "Microdensitometer system with micrometer resolution for reading radiochromic films". The Hong Kong Polytechnic University. 6927859: 1-11. US Patent.
  5. Lee K.Y., Fung K.L. and Kwok C.S. (2004). "Development and initial evaluation of a spectral microdensitometer for analyzing radiochromic films". Physics in Medicine & Biology, 49: 5171-5183.

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